UNLOCK: Unlock this item by beating Mom's Heart 4 times. Pretty much a straight x2 damage up.īeside this, how many items are in the binding of Isaac Rebirth?Īlso Know, how do you unlock the lost? The Lost is unlocked by dying in a Sacrifice Room while holding Missing Poster. Giving you a free devil room every single floor can make your runs super overpowered.
Take no damage on the first hit in any room.
